Process Equipment

The Golden LEAF Foundation provided $13 Million to purchase the initial laboratory, utility, and process equipment for the BEST Center. The North Carolina General Assembly will support the purchase of additional equipment for the drug product manufacturing expansion. A partial list of utility and process equipment is shown below.

Clean Utilities

  • High Purity Water
  • Steam
  • Compressed Air

Support Utilities

  • Waste Neutralization
  • Chilled Water

Cleaning

  • Parts Washer
  • Clean-In-Place
  • Autoclave

Solution Preparation

  • Weigh Booth
  • Single-Use Mixers

Fermentation

  • 15L Stainless Steel Fermenter
  • 150L Stainless Steel Fermenter

Cell Culture

  • 2L Glass Bioreactors
  • 20L Single-Use Bioreactors
  • 50L Single-Use Bioreactor
  • 200L Single-Use Bioreactor

Recovery

  • Centrifuges
  • Depth Filter
  • Stainless Steel Portable Vessels
  • Single-Use Mixers

Purification

  • Chromatography Skid and Columns
  • Tangential Flow Filtration Unit
  • Single-Use Storage Containers
  • Walk-In Cold Room

Bulk Filling

  • Cleanroom Module
  • Horizontal Laminar Air Flow Cabinet

Drug Product

  • Fill Machine in Isolator
  • Manual Filler
  • Capper
  • Visual Inspection Stations
  • Labeler
  • Cartoner